An Enhancer's Length and Composition Are Shaped by Its Regulatory Task
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چکیده
منابع مشابه
An Enhancer's Length and Composition Are Shaped by Its Regulatory Task
Enhancers drive the gene expression patterns required for virtually every process in metazoans. We propose that enhancer length and transcription factor (TF) binding site composition-the number and identity of TF binding sites-reflect the complexity of the enhancer's regulatory task. In development, we define regulatory task complexity as the number of fates specified in a set of cells at once....
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2017
ISSN: 1664-8021
DOI: 10.3389/fgene.2017.00063